Determinants and management approaches for fear of disease progression among stroke survivors

Abstract

This study aimed to identify risk factors for fear of disease progression (FoP) among stroke survivors and propose management strategies. A cross-sectional study of 149 stroke patients (February 2022–March 2025) was conducted using the Fear ofProgression Questionnaire-Short Form, Pittsburgh Sleep Quality Index, Social Support Rating Scale, and Family Adaptability and Cohesion Evaluation Scale II-Chinese Version. Pearson correlations and logistic regression were applied. Clinically significant FoP (≥34) was observed in 45.64% of patients. FoP positively correlated with poor sleep quality and negatively correlated with social support and family functioning (P < .001). Multivariate analysis identified neurological deficit severity, comorbidities, unemployment, and sleep disturbance as risk factors, while older age and higher social support were protective factors. FoP is prevalent among stroke survivors and is associated with sleep quality and social support. Targeted psychosocial and sleep-focused interventions may help reduce FoP.

Medicine - Copyright © 2026 the Author(s). Published by Wolters Kluwer Health, Inc.